| Open Systems Technologies DE, LLC MI | Professional & Technical Services | 1 | $55,000 | - |
| Open Systems Technologies, Inc. NY | Professional & Technical Services | 4 | $98,571 | - |
| Open Systems, INC. GA | Professional & Technical Services | 6 | $82,358 | - |
| Open Technology Fund DC | Other Services | 1 | $165,000 | - |
| Open Technology Solutions, LLC CO | Professional & Technical Services | 1 | $132,848 | - |
| Open Text Inc. MD | Information & Media | 9 | $153,653 | - |
| Open Trade Technology (US) Inc. DE | - | 1 | $91,000 | - |
| Open Water Internet, Inc CA | - | 2 | $157,500 | - |
| OpenAI OpCo, LLC CA | Professional & Technical Services | 184 | $284,100 | - |
| OpenAirInterface Foundation DE | Information & Media | 1 | $135,000 | - |
| OpenBox Solutions, Inc. MI | Professional & Technical Services | 6 | $73,008 | - |
| OpenClinica, LLC MA | Professional & Technical Services | 3 | $102,566 | - |
| OpenCloud IT Solutions Inc TX | Professional & Technical Services | 12 | $112,923 | - |
| Opendoor Labs Inc. AZ | Real Estate | 8 | $325,000 | - |
| Opendoor Labs Inc. CA | - | 0 | - | - |
| Openedges Square CORPORATION CA | Information & Media | 4 | $190,000 | - |
| OpenEvidence, Inc. FL | - | 1 | $325,000 | - |
| OpenGov, Inc. CA | Information & Media | 5 | $87,859 | - |
| OpenGov, Inc. WI | Information & Media | 2 | $124,769 | - |
| OpenInfer, Inc. CA | - | 1 | $185,000 | - |
| Opening Ceremony, LLC (Broadway) NY | - | 0 | - | - |
| Opening Ceremony, LLC (Centre Street) NY | - | 0 | - | - |
| Opening Ceremony, LLC (Howard Street) NY | - | 0 | - | - |
| OpenKyber LLC TX | Professional & Technical Services | 8 | $100,579 | - |
| OPENLANE, Inc. IN | Wholesale Trade | 2 | $195,000 | - |
| OpenLight Photonics, Inc. CA | Professional & Technical Services | 1 | $153,254 | - |
| Openlink Financial LLC NY | Professional & Technical Services | 4 | $122,530 | - |
| OpenLogix LLC MI | Professional & Technical Services | 10 | $107,710 | - |
| Openly LLC MA | Finance & Insurance | 2 | $110,687 | - |
| Openmind Solutions LLC. TX | Professional & Technical Services | 1 | $105,976 | - |
| Openmind Technologies INC CA | - | 1 | $135,699 | - |
| OpenMinds Lab, Inc. CA | Professional & Technical Services | 1 | $86,000 | - |
| Openobserve INC. CA | Information & Media | 1 | $230,000 | - |
| Openphone Technologies INC CA | - | 1 | $250,000 | - |
| Openrxiv CORP. NY | Information & Media | 1 | $87,250 | - |
| Opensoft, Inc. GA | Professional & Technical Services | 1 | $109,429 | - |
| OpenSymmetry, LLC TX | - | 1 | $140,000 | - |
| OpenTable, Inc. CA | Information & Media | 6 | $204,363 | - |
| OpenTable, Inc. CT | Administrative & Waste Services | 6 | $193,375 | - |
| OpenTeQ Technologies LLC TX | Professional & Technical Services | 4 | $119,824 | - |
| Opentrons Labworks, Inc. NY | Professional & Technical Services | 5 | $155,310 | A |
| Openwave Computing LLC. NY | Professional & Technical Services | 6 | $112,923 | - |
| OpenX Technologies, Inc. CA | - | 2 | $70,200 | - |
| Opera Parallèle CA | - | 1 | $139,360 | - |
| Operand Inc. CA | - | 1 | $275,000 | - |
| Operandio US, LLC UT | Information & Media | 2 | $150,000 | - |
| Operation Technology, Inc. CA | Professional & Technical Services | 5 | $136,115 | - |
| Operational Innovations, Inc. NY | Professional & Technical Services | 1 | $105,000 | - |
| Operations Management International INC. TX | Utilities | 1 | $91,484 | - |
| Operations of Global Spectrum, L.P. d/b/a Spectra Venue Management ("Spectra") at Canalside, Buffalo, NY NY | - | 0 | - | - |
