| Openobserve INC. CA | Information & Media | 1 | $230,000 | - |
| Openphone Technologies INC CA | - | 1 | $250,000 | - |
| Openrxiv CORP. NY | Information & Media | 1 | $87,250 | - |
| Opensoft, Inc. GA | Professional & Technical Services | 1 | $109,429 | - |
| OpenSymmetry, LLC TX | - | 1 | $140,000 | - |
| OpenTable, Inc. CA | Information & Media | 6 | $204,363 | - |
| OpenTable, Inc. CT | Administrative & Waste Services | 6 | $193,375 | - |
| OpenTeQ Technologies LLC TX | Professional & Technical Services | 4 | $119,824 | - |
| Opentrons Labworks, Inc. NY | Professional & Technical Services | 5 | $155,310 | A |
| Openwave Computing LLC. NY | Professional & Technical Services | 6 | $112,923 | - |
| OpenX Technologies, Inc. CA | - | 2 | $70,200 | - |
| Opera Parallèle CA | - | 1 | $139,360 | - |
| Operand Inc. CA | - | 1 | $275,000 | - |
| Operandio US, LLC UT | Information & Media | 2 | $150,000 | - |
| Operation Technology, Inc. CA | Professional & Technical Services | 5 | $136,115 | - |
| Operational Innovations, Inc. NY | Professional & Technical Services | 1 | $105,000 | - |
| Operations Management International INC. TX | Utilities | 1 | $91,484 | - |
| Operations of Global Spectrum, L.P. d/b/a Spectra Venue Management ("Spectra") at Canalside, Buffalo, NY NY | - | 0 | - | - |
| Operatus LLC NY | - | 1 | - | - |
| Opers AZ | Accommodation & Food Services | 0 | - | F |
| Opes Solutions LLC FL | Professional & Technical Services | 1 | $116,771 | - |
| OPEX Corporation NJ | Manufacturing | 2 | $137,500 | F |
| Opflex Environmental Technologies NY | - | 0 | - | - |
| OPG Holdings TN | - | 0 | - | - |
| OPH Restaurant Surf City LLC, dba The Original Pancake House CA | - | 0 | - | - |
| Ophir Asset Management US LLC CO | Finance & Insurance | 3 | $232,500 | - |
| Ophthonix Inc CA | - | 0 | - | - |
| Ophthotech Corporation NJ | - | 0 | - | - |
| Opinion Access Corp. NY | - | 0 | - | - |
| Opinr, Inc. DE | Information & Media | 1 | $193,000 | - |
| Opis Renewable Services Inc IL | - | 1 | $75,000 | - |
| OPM Doctors MI | Healthcare & Social Assistance | 1 | $112,341 | - |
| OPmobility KS | - | 0 | - | - |
| OPmobility Exterior USA, LLC MI | - | 2 | $175,000 | - |
| OPmobility f/k/a Plastic Omnium Auto Exterior LLC TN | Manufacturing | 2 | $110,445 | - |
| OPmobility Holding USA, Inc. TN | Manufacturing | 1 | $122,596 | - |
| Oportun, Inc. CA | Finance & Insurance | 18 | $169,494 | - |
| Opp Health & Rehabilitation, LLC AL | Healthcare & Social Assistance | 0 | - | F |
| Opp Health and Rehabilitation, LLC AL | Healthcare & Social Assistance | 0 | - | F |
| Oppenheim Zebrak, LLP DC | Professional & Technical Services | 1 | - | - |
| Oppenheimer & Co. Inc. NY | Finance & Insurance | 2 | $136,866 | - |
| Opperman & Son, Inc. CA | Retail Trade | 0 | - | F |
| Oppermann SC | - | 0 | - | - |
| Oppizi US INC. NY | Professional & Technical Services | 1 | $120,000 | - |
| Opplane INC CA | - | 1 | $140,000 | - |
| Opportune, LLP TX | - | 1 | $135,512 | - |
| Opportunities for a Better Tomorrow NY | - | 1 | $61,800 | - |
| Opportunity Council WA | Healthcare & Social Assistance | 0 | - | F |
| Opportunity Development Centers, Inc. WI | Healthcare & Social Assistance | 0 | - | F |
| Opportunity Financial LLC IL | Finance & Insurance | 3 | $149,005 | - |