| Shippers Transport Express CA | Transportation & Warehousing | 0 | - | F |
| Shipping Done Right Corp. NY | Transportation & Warehousing | 0 | - | - |
| Shiprock Associated Schools, Inc. NM | Educational Services | 4 | $62,400 | - |
| Shipt, Inc. AL | Information & Media | 27 | $152,009 | - |
| ShipTracks, LLC DE | Professional & Technical Services | 1 | $134,500 | - |
| Shipworx Engineering LLC NJ | Professional & Technical Services | 1 | $120,390 | - |
| Shir Capital, LLC TX | Real Estate | 1 | $92,997 | - |
| Shire CA | - | 0 | - | - |
| Shire Human Genetic Therapies Inc. MA | Manufacturing | 7 | $109,970 | - |
| Shire Pharmaceuticals, LLC PA | - | 0 | - | - |
| Shire Regenerative Medicine- Torrey Pines Site CA | - | 0 | - | - |
| Shire Regenerative Medicine- Torreyana Site CA | - | 0 | - | - |
| Shirley Ryan Ability Lab IL | Healthcare & Social Assistance | 0 | - | F |
| Shiro Technologies, LLC TX | Professional & Technical Services | 12 | $94,036 | - |
| SHIROKI North America GA | Manufacturing | 0 | - | F |
| SHIROKI North America TN | Manufacturing | 0 | - | F |
| Shiseido America Inc. NJ | Manufacturing | 0 | - | B |
| Shiseido Americas Corporation NY | Manufacturing | 1 | $220,152 | - |
| Shiv Software Experts LLC VA | Professional & Technical Services | 1 | $114,754 | - |
| Shiva Investments LLC WA | Retail Trade | 2 | $102,513 | - |
| Shivaami LLC NJ | Information & Media | 1 | $82,139 | - |
| Shivam Jewels INC. NY | Wholesale Trade | 1 | $110,240 | - |
| Shivani Technologies LLC GA | Professional & Technical Services | 2 | $86,445 | - |
| Shivers Sweets N Treats NE | - | 0 | - | - |
| SHK Management, Inc. NJ | Real Estate | 0 | - | A |
| SHK Management, Inc. NY | Real Estate | 0 | - | F |
| SHK Management, Inc. PA | Real Estate | 0 | - | A |
| SHL Medical Assembly & Services LLC FL | Manufacturing | 1 | $80,038 | - |
| SHL Medical Design Center LLC FL | Manufacturing | 2 | $79,769 | - |
| SHL Medical US, LLC f/k/a SHL Pharma LLC FL | Manufacturing | 1 | $76,000 | - |
| Sho-Me Power Electric Cooperative MO | Utilities | 0 | - | F |
| Shoals Hospital AL | Healthcare & Social Assistance | 0 | - | A |
| Shoals Technologies Group LLC TN | Manufacturing | 0 | - | C |
| Shock Doctor, Inc. dba United Sports Brands CA | Wholesale Trade | 0 | - | F |
| Shockwave Medical, Inc. CA | Manufacturing | 11 | $189,636 | A |
| Shockwave Medical, Inc. NJ | Manufacturing | 9 | $154,823 | - |
| Shoe Carnival IN | Transportation & Warehousing | 0 | - | B |
| Shoe Palace Corporation CA | Retail Trade | 0 | - | C |
| Shoedazzle.Com, Inc CA | - | 0 | - | - |
| Shoei Foods USA CA | Agriculture & Forestry | 0 | - | F |
| Shoemaker Consulting Engineers, INC. IA | Professional & Technical Services | 1 | $66,000 | - |
| ShoesOff Inc. CA | Information & Media | 1 | $140,000 | - |
| Shoestring Valley Holdings, Inc. OR | Construction | 0 | - | F |
| Shokudo Japanese LLC & Buho Waikiki LLC HI | - | 0 | - | - |
| Shollenbarger-Borello, Inc. CA | Manufacturing | 0 | - | F |
| Shoney's SC | - | 0 | - | - |
| Shook Construction OH | Construction | 0 | - | C |
| Shoolin Inc NJ | Professional & Technical Services | 35 | $98,058 | - |
| Shootsta Inc. CA | Information & Media | 1 | $95,000 | - |
| Shop 'n Save Warehouse Foods (St. Louis area) MO | - | 0 | - | - |
