| Spee Dee Delivery Service, INC IL | Transportation & Warehousing | 0 | - | F |
| Spee Dee Delivery Service, INC MN | Transportation & Warehousing | 0 | - | D |
| Spee Dee Delivery Service, INC ND | Transportation & Warehousing | 0 | - | D |
| Spee Dee Delivery Service, INC NE | Transportation & Warehousing | 0 | - | C |
| Spee Dee Delivery Service, INC SD | Transportation & Warehousing | 0 | - | C |
| Spee Dee Delivery Service, INC WI | Transportation & Warehousing | 0 | - | F |
| Speechify, Inc. FL | Information & Media | 3 | $374,667 | - |
| Speed Construction and Development Inc. CA | Construction | 1 | $81,182 | - |
| Speed Wrench Inc MI | Other Services | 0 | - | D |
| Speedbox LLC CO | Transportation & Warehousing | 0 | - | F |
| Speedco OK | Retail Trade | 0 | - | D |
| Speedling, Inc FL | Agriculture & Forestry | 0 | - | A |
| Speedrack Products Group Ltd MI | Manufacturing | 0 | - | F |
| Speedway Construction Products Corporation IN | Transportation & Warehousing | 0 | - | C |
| Speedway Motors NE | Transportation & Warehousing | 0 | - | A |
| Speedway Motors WV | Transportation & Warehousing | 0 | - | F |
| Speedy Concrete Cutting, Inc. FL | Construction | 0 | - | F |
| Speedy Gonzalez Delivery Services, LLC WA | Transportation & Warehousing | 0 | - | F |
| Speedy Romeo LLC NY | - | 0 | - | - |
| Speedy Stop Food Stores TX | - | 0 | - | - |
| Speer Mechanical OH | Construction | 0 | - | B |
| Spekle Solutions, Inc. CA | Professional & Technical Services | 3 | $152,333 | - |
| Spektrum Brakes, LLC CA | - | 0 | - | - |
| Spellman High Voltage Electronics Corporation NY | Manufacturing | 3 | $122,443 | A |
| Spelman College GA | Educational Services | 2 | $59,460 | A |
| Spenard Roadhouse AK | - | 0 | - | - |
| Spencer Building Maintenance CA | Administrative & Waste Services | 0 | - | F |
| Spencer Construction AZ | Construction | 0 | - | A |
| Spencer Construction, LLC CA | - | 0 | - | - |
| Spencer Gifts LLC NJ | Retail Trade | 5 | $158,221 | - |
| Spencer Industries IN | Manufacturing | 0 | - | D |
| Spencer Industries Inc IA | Manufacturing | 0 | - | F |
| Spencer Municipal Hospital IA | Healthcare & Social Assistance | 0 | - | F |
| Spencer N. Enterprises, Inc. CA | - | 0 | - | - |
| Spencer Ogden Inc. TX | Administrative & Waste Services | 1 | $57,500 | A |
| Spencer Outdoor LLC TX | Administrative & Waste Services | 0 | - | D |
| Spencer Stuart Star US, Inc. IL | Professional & Technical Services | 1 | $123,600 | - |
| Spencer//Butcher Group MI | Transportation & Warehousing | 0 | - | B |
| Spencer/Butcher Group Assemble Rite Ltd. MI | - | 0 | - | - |
| SpencerARL New York, Inc. NY | - | 0 | - | - |
| Spenco Medical Corporation TX | - | 0 | - | - |
| Spendgo Inc. CA | Professional & Technical Services | 2 | $155,605 | - |
| Spenuzza Inc - Imperial Manufacturing CA | - | 0 | - | - |
| Speridian Technologies, LLC NM | Professional & Technical Services | 38 | $102,952 | - |
| Speriti Solutions LLC TX | Professional & Technical Services | 1 | $98,946 | - |
| Spero Academy MN | Educational Services | 2 | $63,227 | - |
| Sperry & Rice Manufacturing OH | - | 0 | - | - |
| Speyside Bourbon Cooperage in Virginia, Inc. VA | - | 0 | - | - |
| Speyside Bourbon Cooperage, Inc. VA | Manufacturing | 0 | - | F |
| Speyside Bourbon Cooperage, Inc. VI | Manufacturing | 0 | - | F |
