| Upstage Acquisition, LLC TX | Administrative & Waste Services | 0 | - | F |
| Upstage Center Inc. TX | Administrative & Waste Services | 0 | - | F |
| Upstart Network, Inc. CA | Finance & Insurance | 41 | $180,095 | - |
| Upstate Caring Partners NY | Healthcare & Social Assistance | 0 | - | F |
| Upstate Carolina Medical Center SC | - | 0 | - | - |
| Upstate Cerebral Palsy NY | Healthcare & Social Assistance | 0 | - | F |
| Upstate Recycling LLC NY | Wholesale Trade | 0 | - | F |
| Upstate SC Logistics LLC SC | Transportation & Warehousing | 0 | - | B |
| Upstate Services Group NY | Healthcare & Social Assistance | 0 | - | F |
| Upstate Shredding NY | Wholesale Trade | 0 | - | D |
| Upstate Steel Inc. NY | Wholesale Trade | 0 | - | D |
| UpStream Care Company NC | - | 0 | - | - |
| Upstream Vision LLC TN | Professional & Technical Services | 1 | $83,464 | - |
| Uptick Software US INC CA | Information & Media | 1 | $137,000 | - |
| Uptik Solutions Inc TX | Professional & Technical Services | 2 | $127,878 | - |
| Uptiq INC. TX | Information & Media | 3 | - | - |
| Uptown Airport Group LLC NC | - | 0 | - | - |
| Uptown Bake & Brew LLC MD | Manufacturing | 0 | - | F |
| Uptown Chevrolet-Cadillac, Inc. NY | - | 0 | - | - |
| Uptown Collab MN | - | 0 | - | - |
| Uptown Healthcare Center CO | Healthcare & Social Assistance | 0 | - | - |
| Uptown Productions, Inc. - Burbank Studios CA | - | 0 | - | - |
| Uptown Productions, Inc. - Paramount Lot CA | - | 0 | - | - |
| Uptown VFW MN | - | 0 | - | - |
| Uptown Westerville Healthcare OH | - | 0 | - | - |
| Uptrend Technologies LLC MD | Professional & Technical Services | 9 | $92,754 | - |
| Upturn Business Inc. CA | - | 0 | - | - |
| Uptycs, Inc. MA | Professional & Technical Services | 1 | $108,200 | - |
| Upward Innovations LLC TX | Professional & Technical Services | 4 | $86,664 | - |
| Upward Logistics Group LLC TX | Transportation & Warehousing | 0 | - | F |
| Upward Systems Inc TX | Professional & Technical Services | 1 | $80,746 | - |
| Upway USA, Inc NY | Other Services | 1 | $169,600 | - |
| UpWest MN | - | 0 | - | - |
| Upwind Security, Inc. CA | Information & Media | 1 | $230,000 | - |
| Upwing Energy, Inc. CA | Professional & Technical Services | 2 | $122,500 | - |
| Upwork Global LLC CA | Professional & Technical Services | 11 | - | - |
| Upwork, Inc. CA | Professional & Technical Services | 10 | $220,714 | - |
| Upwork, Inc. IL | - | 0 | - | - |
| UR International, Inc. TX | Professional & Technical Services | 3 | $107,333 | - |
| UR Medicine Thompson Health NY | Healthcare & Social Assistance | 0 | - | F |
| Ur Technologies INC MN | Professional & Technical Services | 2 | $96,803 | - |
| Urata & Sons Concrete, LLC CA | Construction | 0 | - | F |
| Urbahn Architects PLLC NY | Professional & Technical Services | 2 | $77,126 | - |
| Urban Alchemy CA | Other Services | 0 | - | F |
| Urban Alchemy (8th Street Shelter) TX | - | 0 | - | - |
| Urban Alchemy (Arch Shelter) TX | - | 0 | - | - |
| Urban Architectural Initiatives, RA, P.C NY | Professional & Technical Services | 3 | $90,036 | - |
| Urban Chalet, Inc. CA | Professional & Technical Services | 1 | $70,000 | - |
| Urban Christian Academy IL | Healthcare & Social Assistance | 1 | $43,763 | - |
| Urban Circle Realty INC MA | Real Estate | 1 | $84,500 | - |