| Isle of Capri Casino Boonville d/b/a IOC-Boonville, Inc. MO | — | 0 | — | — |
| Isle of Capri Casino Kansas City MO | — | 0 | — | — |
| Isle of Capri Casinos MS | — | 0 | — | — |
| Isle of Wight County VA | Public Administration | 0 | — | C |
| Isle Parkway Apartments AL | Real Estate | 0 | — | A |
| Isles of Boynton Nursing and Rehabilitation Center FL | Healthcare & Social Assistance | 0 | — | F |
| ISLF DEERWOOD PLACE JACKSONVILLE LLC FL | Healthcare & Social Assistance | 0 | — | F |
| ISLF REGENTS PARK WINTER PARK LLC FL | Healthcare & Social Assistance | 0 | — | F |
| ISLF WESTCHESTER OF SUNRISE LLC FL | Healthcare & Social Assistance | 0 | — | A |
| ISM Restaurant Services WI | Administrative & Waste Services | 0 | — | A |
| ISMAEL LEYVA ARCHITECTS, P.C. NY | Professional & Technical Services | 2 | $62,000 | — |
| Ismail B. Sendi, M.D., P.C. MI | Healthcare & Social Assistance | 2 | $73,475,948 | — |
| ISN Software Corporation TX | Information & Media | 8 | $140,625 | — |
| Isna Wica Owayawa SD | Educational Services | 1 | $43,000 | — |
| ISO New England, Inc. MA | Utilities | 5 | $143,269 | F |
| Iso-Med, Inc CA | Wholesale Trade | 0 | — | A |
| Isoclima Specialty Glass AL | Manufacturing | 0 | — | C |
| Isoclima Specialty Glass PA | Manufacturing | 0 | — | F |
| ISOFlex Packaging WA | Manufacturing | 0 | — | C |
| iSoft LLC CT | Professional & Technical Services | 1 | $85,000 | — |
| ISOFTECH INC VA | Professional & Technical Services | 9 | $112,666 | — |
| iSoftStone, Inc. TX | Professional & Technical Services | 2 | $83,369 | — |
| iSoftStone, Inc. WA | Information & Media | 2 | $60,000 | — |
| Isola Group SC | Manufacturing | 0 | — | C |
| Isola USA Corp. AZ | Manufacturing | 0 | — | A |
| ISOLA USA Corp. CA | — | 0 | — | — |
| Isolatek International CA | Manufacturing | 0 | — | F |
| Isolatek International IN | Manufacturing | 0 | — | A |
| Isolatek International NJ | Manufacturing | 0 | — | B |
| Isolatek International TX | Manufacturing | 0 | — | A |
| Isolve Technology Inc VA | Professional & Technical Services | 30 | $107,759 | — |
| iSolvers, Inc. FL | Professional & Technical Services | 2 | $107,412 | — |
| Isometric Companies, Inc. WI | Professional & Technical Services | 0 | — | A |
| Isometric Micro Molding, Inc. WI | Manufacturing | 0 | — | A |
| Isometric Tool & Design, Inc. WI | Manufacturing | 0 | — | A |
| Isometrics, Inc. NC | Manufacturing | 0 | — | F |
| IsoNova Technologies LLC SC | Manufacturing | 3 | $146,667 | — |
| Isoray Medical WA | Manufacturing | 0 | — | A |
| Isosceles Holdings IL | Construction | 0 | — | B |
| Isotec International, Inc. GA | Manufacturing | 0 | — | F |
| Isotek Systems LLC TN | Public Administration | 0 | — | A |
| Isovolta OR | Manufacturing | 0 | — | A |
| Isovolta, Inc. VT | Manufacturing | 0 | — | A |
| Isowa America, Inc. AZ | Wholesale Trade | 0 | — | F |
| ISP Freetown Fine Chemicals Inc. MA | Manufacturing | 0 | — | B |
| ISP Technologies Inc. (DBA Ashland Inc.) TX | Manufacturing | 0 | — | B |
| Isp, Innovative Surgical Products CA | — | 0 | — | — |
| ISPACE, INC. CA | Professional & Technical Services | 2 | $106,496 | — |
| iSpace, Inc. NJ | Professional & Technical Services | 5 | $103,000 | — |
| ISPERO LLC IL | Professional & Technical Services | 4 | $93,446 | — |
