| Little Amerricka Amusement Park LLC WI | Arts & Entertainment | 0 | — | A |
| Little Big inch Pipeline TX | Construction | 0 | — | C |
| Little Blessings NE | — | 0 | — | — |
| Little Brook Nursing and Convalescent Home NJ | Healthcare & Social Assistance | 0 | — | F |
| Little Brother's Bakery, LLC CA | Manufacturing | 0 | — | D |
| Little Brown Mouse Plumbing OH | Construction | 0 | — | A |
| Little Caesar Enterprises, Inc. MI | Manufacturing | 1 | $132,692 | — |
| Little Chute Health Services WI | Healthcare & Social Assistance | 0 | — | F |
| LITTLE CREEK AG, LLC GA | Agriculture & Forestry | 0 | — | A |
| Little Darlings of Las Vegas NV | Arts & Entertainment | 0 | — | A |
| Little Dixie C.A.A., Inc. OK | Healthcare & Social Assistance | 0 | — | A |
| Little Dixie Construction, LLC MO | Construction | 0 | — | A |
| Little Dutch Boy Bakeries UT | Manufacturing | 0 | — | B |
| Little Eden LLC CA | Educational Services | 1 | $58,120 | — |
| Little Enterprises Inc. AZ | Construction | 0 | — | A |
| Little Enterprises LLC MA | Manufacturing | 0 | — | A |
| Little Enterprises North ME | Manufacturing | 0 | — | F |
| Little Falls Alloys INC NJ | Manufacturing | 0 | — | A |
| Little Falls Care Center MN | Healthcare & Social Assistance | 0 | — | F |
| Little Falls Hospital NY | Healthcare & Social Assistance | 0 | — | F |
| Little Falls Lumber Co Inc NY | Construction | 0 | — | A |
| Little Falls Machine, Inc. MN | Manufacturing | 0 | — | F |
| Little Fishermen's Fish and Chips Inc CA | Retail Trade | 0 | — | A |
| Little Flower Manor PA | Healthcare & Social Assistance | 0 | — | F |
| Little Flower Montessori School LLC FL | Educational Services | 0 | — | A |
| Little Friends, Inc. IL | Healthcare & Social Assistance | 0 | — | F |
| Little Goat, LLC dba Little Goat IL | — | 0 | — | — |
| Little Guys Movers, Inc. AR | Transportation & Warehousing | 0 | — | F |
| Little Guys Movers, Inc. CO | Transportation & Warehousing | 0 | — | F |
| Little Guys Movers, Inc. NC | Transportation & Warehousing | 0 | — | F |
| Little Guys Movers, Inc. OK | Transportation & Warehousing | 0 | — | F |
| Little Guys Movers, Inc. TN | Transportation & Warehousing | 0 | — | F |
| Little Guys Movers, Inc. TX | Transportation & Warehousing | 0 | — | F |
| Little Harbor Window ME | Manufacturing | 0 | — | D |
| Little Island NY | Arts & Entertainment | 0 | — | D |
| Little Kids Inc. MA | Manufacturing | 0 | — | A |
| Little Lady Foods IL | Manufacturing | 0 | — | B |
| Little Leaf Farms MA | Agriculture & Forestry | 0 | — | F |
| Little Leaf Farms LLC PA | Agriculture & Forestry | 0 | — | F |
| Little League Baseball, Incorporated PA | Arts & Entertainment | 0 | — | C |
| Little Linda Bus Co. Inc. NY | — | 0 | — | — |
| Little Linda Matron Co. Inc. NY | — | 0 | — | — |
| Little Lisa Bus Co. Inc. NY | — | 0 | — | — |
| LITTLE LISA INC PA | Manufacturing | 0 | — | F |
| Little Lisa Matron Co. Inc. NY | — | 0 | — | — |
| Little Man Farming INC NC | Agriculture & Forestry | 0 | — | A |
| Little Miami Construction Company OH | Construction | 0 | — | A |
| Little Mountain Precision LLC OH | Manufacturing | 0 | — | F |
| Little Mountain Printing, Inc. PA | Information & Media | 0 | — | F |
| Little Pappas Seafood House TX | — | 0 | — | — |